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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6b222ca0c759146a343b647bfc2562a2b46e3e8713384510602befc35ac44a' 
  AND token = 'bn6v5hjoFfkffWE4mgBZFiLOzhX+FkugxtB4IiGj0ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}