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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f4320e46a2028f69a57d04f19ba2f81c018d92cf581c831636001e71f1865e' 
  AND token = '0uD8d9NUSpSMoGmWDuKG7D+37GV/JVKkqEh52BsG8Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}