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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d17c65aab1180acf458600cc4d967f9e49a331190376ad17924357bb4b2e5a' 
  AND token = 'lCFkaGSeKc8sKBwVrynrkDE2sd6yDc6lPP1KWZdvHcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}