SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f58f32f73d6f4ce493b19534a1f1ab10aa6311a280568dd2b2a4c48a5a850c2' 
  AND token = 'lkFzXgsyyZxH43fUYCWL4vsNnGKXfa+mC4jWMAmcjm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}