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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73985ab8022c9b77bc3d711262e3c60737fed1d24d059ddf011c72ec3e1fe9b' 
  AND token = 'LyfkWYNX4N/xPT/1RGWAWtA4oBBWfKGGjBJsQ8uXhAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}