SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35f946e45594182e4ca50bbe83ac8c3d84edac4f16a3a00db4531f7c422f95fc' 
  AND token = 'MYdLNU++xCVBFRg4EC0M5XHkT4c/nQn0qMwBp9vHL3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}