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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225fcf861baefa90582402f940a08123ffccbb9d73f5a6abdf8195230d9b8730' 
  AND token = 'Bo7xn/fBpM1YgUuMvQ5yc4Tr4N9yjQjYA7KI/Xbhhm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}