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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcc99c986f75e3d422a85c61d29b1d5c3a2819870d24617e23181d763e23b768' 
  AND token = 'Az3a8Go2MjamFWOsayvfgTyjCyBNRHUzGN1fZKWLzHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}