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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b003e62abd9c76f8bdc4b5564b81e3aa75729fcf74507ac89bec2cd6e6517a6' 
  AND token = '1iay4WE7brZntL7+8bTxsNvwTukN49ZZXiW4bk4MIs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}