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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de983e22d88e6b224c5f47acb9a52e62f7e7695b5c3d50cb67609ae75806c67' 
  AND token = 'XRqhDKaLmADu1c77fTTuLMxrpVO4zfy5BBPwT5wpb7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}