SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef686ffff300169b2ef52d4211e1b6eec5a1a26dc01fa648546c21c6993e270' 
  AND token = 'r33PU3LKbzvOXczsb4030qRYuB0IxuWq+5CSvs3UEm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}