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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f963b451eb079e63b35d639a9ff539066a2ae0d913d9b48d3d79c9a8fb53b0c' 
  AND token = 'PR0yT4x5COEM8MbrvxHX2AX/mPLw8ZI30Fyqr/klDW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}