SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4f76c6e74b8e778b64754022d6fb71fbe2068301dd7b457293ebb98ea84398' 
  AND token = '+mtwyB3EUbxEp2X5/YdkYX2r9bybiowIk0SvpDl/G5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}