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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218d41299d9e1ce39b77f62eb27094c4fb32f2344662eb4d05d057ce0ed122bb' 
  AND token = 'TmiQKFMrR4YZwN/BRCX6QHQvKuRh5feR8wXvDixukRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}