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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65fb2036cc910a2347da0a3f1727dfcde0d2e3498fc9b23a625e75b5984e002' 
  AND token = 'Jjkiaau7kGjXAVqH+S4akOyNEKVZpPDGFEAMT8JdzbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}