SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42754be780d89fa137fb38b2c6051c6ea5e94724ea64cc38e76dc2b5ca177432' 
  AND token = '3n39V4UzxkxjZZ6Vaepggj/U8N22MxYtngxxAMNqVW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}