SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc24633dfd50c8d2543549b26fc5925a13ac2d47e0a889159492f089cadb0a09' 
  AND token = 'V8PCF1tTHcKQzrnXfWQuF1q9IIAXcOtLiAfJdTT1j6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}