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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8e515c2bf3ab45c738d8ab9117f037034ea0d114c772ada69607a6c9796408' 
  AND token = 'bZxO2IZFv2KcnPxIurnvgWy5OdgY9FzoQZrxH26Ri/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}