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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35fbf5cdb67988a23e183295e5ad385da8d5e76b0dd1e73978858385390777f' 
  AND token = 'jV1no2CcrW4+FdH0CiZNhoUvVm9duqbjXB0Y7/sObdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}