SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80013004b5371b303fc2baad98823ed8cb3cabd9d7f1fd4dd05078a0af60693' 
  AND token = '/zmkVJ440eFGivTBJertxrjwnNMeSxnq9TU9wF+hlJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}