SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f657853870c02bb0eaa7d2c7a4e9072e69947e1511ac6aea3a8123d9e7b6f730' 
  AND token = 'CKR2I8ZQU3EbD+G2p1MBhJfhbP2RPlbU4FiLXckPXvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}