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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb185541be4c9dc99e5553dc98b60810250ff9f80f83698a7f25193cf9da8a0' 
  AND token = 'OaCvn9jOL9P72LAQUk5vmjffJZasuseEisjBrEYDJIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}