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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e587d4999b0ad6015d82a6b54cde3005882f13b8f389aa2c8fd0a46d42df80a2' 
  AND token = 'Quk3g6VCN4a6fjPaQbADRBTnslTh++xhkf1T9/nlLvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}