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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '109627ebe669ba2af04d80971060084785bb4dfed8a621f72d6af9cf16adcf59' 
  AND token = 'U3MuH/boqyvS/+fGsMNUJHRZlcfnEGxPK+dda8H+p9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}