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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643ee73774034eae7fec2ff39ae65ab75d1db4ded4e0ca6ef061e27af1c74f82' 
  AND token = '2ORjuCTYtsJRTJrJUhVBSXb0/IgoGvcGtBRMVwGYz1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}