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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99505373634adf7a52b8c634f1f8bcc1a8e5ff9ad042f938d42c1a9710a02e90' 
  AND token = 'ED1Y3jUf2j0E2wZDfh+W5IEL/NTq7jHm69sMdVwlDgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}