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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59366e2dfd9a7154b674b109740748a5deafdac3a0427f810e0e3611faffb320' 
  AND token = '8OTiAIGmCAZzYyaDLFt9lPGCZ0tqud/+JfV33rRl8U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}