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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e1c95ce1b3d0f9ed4e5e5ec013750637eb4a65c79c908d680f34aad66a7289' 
  AND token = 'VDP/Mkf9GjPxHEhu/uB7Ak69usW/SR1YPVIhWPbkEaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}