SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6165f95fdcd5823799d64111083223b086c38ddc6c303b12c0442e08ccfb94' 
  AND token = 'OtqUkxu809jJdnFx7NjXM9aBvGHh7onnSEuE9XOZ4uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}