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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de73cbc7207f798aa8140f57ea3f9a0145f8855fece9428b9d081346587900e' 
  AND token = 'KmStEeXKuGB3Ez/FFUkBklPXL3nAePbVcR/x+Kxf3/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}