SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60281afff27821403eee6d81d01081b5b32a01fa354cd26d7b415b8b96feb900' 
  AND token = 'ureg3NkSpXNmRJjPAEMfcGPA9ZV85WA4jpaJv8d2RMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}