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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f7de3481814609f8fa874feb83e2dbf06506ee630f49add88b08d485003b87' 
  AND token = 'jM/m52tG7JvQZcr4EvvPGjaG68zsmcFQ7C9pJppxnPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}