SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed6edb9aed3d94b539fe72a0b09046d59cc892c4e114401fdbaab9126110251' 
  AND token = 'vXtF8f5r04RIN9DeUZ3Pu618fGY6j0D5+XW0atOqZ1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}