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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0cd6517cc86e931c9153c42ba5bef0a6dd3345da6798e47d29ff232fd70f771' 
  AND token = 'dEFlhcGxrizDTcxlCPttWMzDU/0bVz0CETDYZWsxkhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}