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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b17808c9afcf1ed1fedaeb292f76ae4535dac964d867bc79c624b5288a9a037' 
  AND token = '9zUKIxXLIWkdr7gt23SF2GNeqmJgdbKnMJl/ix8fb3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}