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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc46dcfac23c2c58216ba2ea37f0271f3801214475cdcc920bf65a1ace90a7d' 
  AND token = 'oZ0VmZ2plQX5JoCzNzMGhf4RLKkN0eViy0WiI3Yys7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}