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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '156861f4c722802f47284a36a4579ab2eab03905f94de9a32b1e1aa8165d853d' 
  AND token = '67A/Zw8+euDwFmSpsDOY68jbNXHraACsrSibl535ciE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}