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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1ef193ed4aacc354e65630ac5a428c21275019ac902a0fc4f7da8a33925be4' 
  AND token = 'IcBpJkSFEPINMRVoJFBayMuVZnOrStJDDoQcEIT0qdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}