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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0cec6baf2f1c74ff5062a4e8ffc988396cf050de0ba46c1a1f61f1358fe948' 
  AND token = 'T4TIAZv8BvvQLt5/6SRZAjMOt4aCjAFeQnMKYO3LMlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}