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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d00597c5acc7b58ab49ee3f36155f89eedfb23aa397d9b23603b7af22f791a1' 
  AND token = 'H+U0vwkrO3qMOfE5VhUn8wDXMqAqmphT3Q8jQsUY3qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}