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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c8f910cff6f6dc949744693bba3f6bda5b665c7e91bed208989224b6d52035' 
  AND token = '8HYUDt0vPf7GbmXxJcGAthhYb3JANBhb7HUK3xvNPxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}