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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531f3da7cb6c75664e06db203ca4158d87e5d705d9b7d473f31346264cbfdf5b' 
  AND token = 'VT/x6hWVfQIOh5O269c9lYYhbhjaS+uGA150cP+p0SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}