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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1b67f7126974a6e7027c2a0f844b3d4d192bf9f594eb767f3f36a897ced7c4' 
  AND token = 'qYWU1m2s8FIs5sebt9r6VZUxRTrcVEpi624gZQ8mIZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}