SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9925a64d56be7b6740582627b871b4d74877f54364edf9262a640da79042ce' 
  AND token = 'bCJvIPqaeWjlkroyAe2T9GSW5dga2FVZDVKFiEn4uGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}