SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfbe7244f7f5db6e6f87b09bbcd9a8cba4a137353c79b31bc96711a918642da' 
  AND token = 'YU5BIGRDzjbagVx8zyTT/uJSQNKqcezV0E/dJVwFnqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}