SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e366d84d6355e0c034ec4b32e2459f16d1f0527dc5855be7bbdb22301b8076' 
  AND token = 'uOteGZhjeb7YqlNSDxvSOH5FMUWYdo7o1YfiDDqf4F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}