SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6e63f5745a38cb628ce7cacee3badbcd0bfbc88b1e4d9b84c54f128a5ed653' 
  AND token = 'G8Qj21ySmOoOP2uuomum3hLokJisMxt8/6L1F606Oic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}