SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6427bc1f77edee9febb88134b30ebe5440e3bed3249537c7e2885bad1ad7e64' 
  AND token = 'PjidaNz/8kfc9VrGLA+qKByjORbmIhO97A9zE8nSzwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}