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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7bf7be081fb57effa8fd6be6245e3e301da0a2a4b7bdb092f3442e329837170' 
  AND token = 'pLyCU7qP8AWY9L7n87UXNYFS+GnORs4qm9D316g+6Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}