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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec20a687d0805ed41d1747b5003603d1428cd4324ea5bde48958cd61495e23fc' 
  AND token = '3x6tDurIJYBY7zESC1sj4EzNNHDREutWxl/0XShvKq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}